Being able to sense and process environmental cues is among the most fundamental requirements of life and thus not only restricted to the specialized cells that we use to smell and taste. In fact, a team of scientists from Monasterium Laboratory, the University of Miami (USA) and the University […]
A team of researchers from the University of Manchester, University of Miami, and Monasterium Laboratory in Münster, Germany, have recently reported a novel methodology that closes an important gap in current hair research technology. The study published in the journal Archives of Dermatological Research1 identifies a pragmatic, elegant and instructive […]
Compartmentalised metabolic programmes in human anagen hair follicles: New targets to modulate epithelial stem cell behaviour, keratinocyte proliferation and hair follicle immune status? Purba et al. Exp Dermatol 2021 Lactate, the end-product of aerobic glycolysis (Warburg effect), is important for much more than just energy metabolism and is now recognized […]
Once again the founders of Dermasphere Dr. Luke Johnson, University of Utah School of Medicine & Dr. Michelle Tarbox, Texas Tech University Health Sciences Center talked to our founder & CEO Prof. Paus and discussed on the crucial topic of “Chemotherapy-induced alopecia areata”. Listen to the recent podcast on SoundCloud. […]
Investigations revealed the significance of the overlooked population of T-cells—the Gamma-delta-T-cells (γδT-cells)—in Alopecia Areata pathogenesis1 Our skin contains a varied population of T-cells, the crucial elements of the immune system that perform surveillance on specific foreign bodies. Even so, sometimes instead of protecting, they turn into a self-attacking mode, which […]
Re-innervation of human skin by rat dorsal root ganglia permits to study interactions between sensory nerve fibres and native human dermal mast cells ex vivo. Chéret J. et al., Exp. Dermatol., 2021 Despite several practical benefits, human skin organ cultures typically suffer from denervation—a loss of nerve supply. It hinders […]
Listen to the podcast (link below) where our founder & CEO, Prof. Ralf Paus shares his passion for hair follicles, the most dynamic mini-organ in the human body. In this podcast, he touched upon various topics ranging from the role of the chemosensory olfactory receptor system and its impact on […]
Please tell us a bit more about the Monasterium Laboratory biobank! As we all know, the skin is the largest organ of the human body and it has many important and crucial functions except just having a decorative role. It acts as a protective barrier between the outside and the […]
Topical odorant application of the specific olfactory receptor OR2AT4 agonist, Sandalore®, improves telogen effluvium associated parameters. Jimenez. F et al., J Cosmet Dermatol, 2020 Excess hair shedding called telogen effluvium is one of the most common complaints in women yet there are few clinically demonstrated cosmetic solutions available. In this […]
It is our pleasure to proudly share that we have cleared another important milestone in the short, but memorable history of Monasterium Laboratory – Skin & Hair Research Solutions GmbH. Today our research company reaches its 5th anniversary since establishment in 2015. To mark this date, we have launched our […]
Anti-aging skincare research is a major topic in the cosmetics and nutraceuticals industry. There is a huge market demand and competition globally to develop novel products and strategies that tackle causes and signs of skin aging. Scientists in industry and academia are studying the underlying key signalling pathways and mechanisms […]
Monocyte (MO)-derived macrophages (MACs) and self-renewable tissue-resident macrophages (tr-MACs) play an important role in regulating and maintaining MAC pool during inflammation in murine skin (1). However, our current understanding of MACs origin and their differentiation in peripheral tissues is limited to murine studies and the existence of such activities […]
We are glad to share that many of our team members who are the scientific experts in the field of skin & hair research have contributed to some of the chapters in the recently published book, Molecular Dermatology - Methods & Protocols by Springer Protocols. We believe that this book […]
Theophylline exerts complex anti-aging and anti-cytotoxicity effects in human skin ex vivo. Bertolini. M et al., Int J Cosmet Sci, 2020 The detailed insights of the effect of theophylline on human skin are poorly understood. Here, we show that theophylline possesses several striking complex skin-protecting properties in human skin […]
