Research Highlights
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Adenosine promotes human hair growth and inhibits catagen transition in vitro – role of the outer root sheath keratinocytes.Lisztes E et al., J Invest Dermatol, 2020It is well known that adenosine promotes human hair growth. In this study, together with our Hungarian collaborators, we unravel a novel mechanism by which adenosine regulates hair cycle. In […]
It is long known that adenosine promotes hair growth. One of the proposed mechanism involves the regulation of hair cycle-associated growth factors production and release by dermal papilla fibroblasts. However, full characterization of the cellular mechanism by which adenosine regulates hair growth cycle, and the distribution of adenosine receptors (ARs) in human hair follicles […]
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An osteopontin-derived peptide inhibits human hair growth at least in part by decreasing FGF7 production in outer root sheath keratinocytes. Alam M. et al., Br J Dermatol, 2019 Osteopontin, a multifunctional immunomodulatory glycoprotein is expressed in human hair follicles. In this study a peptide fragment of OPN, FOL005 was investigated for impact on hair growth […]
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Previous studies examining the topical application of theophylline in murine skin showed photodamage-protective properties (1). However, the effects of theophylline on human skin remains elusive. By using cutting-edge microscopy techniques and ex vivo assays, the research team at Monasterium Laboratory GmbH has investigated the in-depth effect of theophylline administration on human scalp skin. The study […]
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