New services

Pathological wound healing ex vivo model

In New services by Abhiyan Viplav

Wound healing is a highly complex dynamic process that involves the activation of several signalling pathways. In case of pathological environment such as age, diabetes and cancer, wound healing becomes more critical and can be chronically disrupted. We have developed …

Scalp UV irradiation ex vivo assay

In New services by Abhiyan Viplav

To understand the impact of UV (ultraviolet) irradiation on human hair follicle homeostasis is very important. We have developed a new ex vivo assay to investigate how solar UVR that hits the human scalp skin surface effects hair follicle physiology. …

Lipidomics analysis of human hair follicle and hair shaft

In New services by Abhiyan Viplav

We collaborate with Lipotype GmbH, Dresden Germany and have established a novel technique to perform high-resolution shotgun lipidomics analysis on micro-dissected human hair follicles. Together with our partner, we can investigate effectively whether any compound or formulations affect the lipid …

Advanced label free-optical coherence tomography

In New services by Abhiyan Viplav

In collaboration with the team from Biomedical Technology Center, University of Münster, we have developed an advanced intra-vital method to obtain high-resolution anatomical details of micro-dissected human hair follicles based on the label free-optical coherence tomography technique. This method allows …

Complete skin re-innervation model

In New services by Abhiyan Viplav

Human scalp skin and hair follicles (HF) are densely innervated by sensory peripheral nerve fibers (NF). This crosstalk between skin and nerves suggests that neuro-mediators released by cutaneous NFs effect human epidermis and HF function and vice-versa. Imbalance in this …

Human atopic dermatitis mouse model

In New services by Abhiyan Viplav

We collaborate with Prof. Dr. Amos Gilhar, Technion Israel Institute, Israel to develop a novel humanized mouse model for atopic dermatitis (AD). Our AD model recapitulates all the key features of the disease that are required for the preclinical development …

Chemotherapy- induced alopecia humanized mouse model system

In New services by Abhiyan Viplav

Chemotherapy-induced alopecia (CIA) causing permanent or partial hair loss in the course of chemotherapy, is a major non-desirable effect of most systemic cancer treatment therapies. To advance our knowledge from our established chemotherapy-induced alopecia ex vivo model towards more clinically …